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10.
Am J Physiol Lung Cell Mol Physiol ; 317(6): L785-L790, 2019 12 01.
Artigo em Inglês | MEDLINE | ID: mdl-31577160

RESUMO

Fritz Rohrer (1888-1926) has a special place in the history of respiratory physiology for two reasons. The first is that he laid the foundations of modern pulmonary mechanics in the early 1900s. For example, his seminal paper on pulmonary dynamics, that is, the pressure-flow relationships in the airways, was published in 1915 in one of the top journals in the field. It included extensive measurements of airway dimensions in postmortem human lungs and a sophisticated analysis of the modes of airflow. This was closely followed by a very original analysis of lung statics, which included studies of airway pressures at normal, maximal, and minimal lung volumes in relaxed normal volunteers, and was published in 1916. Remarkably, both papers were essentially ignored at the time. Fortunately, in 1925 he was able to summarize his major findings in a chapter in an important handbook of physiology. However, he tragically died from pulmonary tuberculosis in the following year at the early age of 37. The second reason for his importance in the history of pulmonary mechanics is that inexplicably his very innovative research was essentially ignored for about 30 years. It was not until the 1940s that his work was rediscovered, although not in time to save investigators from duplicating his very original studies. Possible reasons why his work was ignored for so long are discussed. Even today it is not easy to recover some important features of his career, and some aspects of his very original research are still almost unknown.


Assuntos
Pneumologia/história , Mecânica Respiratória , Sistema Respiratório/fisiopatologia , História do Século XIX , História do Século XX , Humanos
12.
Eur Respir J ; 54(2)2019 08.
Artigo em Inglês | MEDLINE | ID: mdl-31273040

RESUMO

The Global Initiative for Asthma (GINA) was launched in 1993 under the auspices of the National Heart, Lung, and Blood Institute, National Institutes of Health, USA, and the World Health Organization to produce a global strategy on asthma management and prevention. Now constituted as a non-profit entity, it continues to produce, on an annual basis, the most widely cited evidence-based report on the optimal management of asthma in both adults and children intended for global use. Although the GINA Report is often viewed and used as an asthma treatment guideline, it is designed to be a clinically oriented strategy document that supports the development of practice guidelines in different countries and regions.Other GINA products, including the report's pocket guides, teaching slide kits and implementation tools, are also offered free of charge for public use. The GINA Scientific Committee comprises recognised international experts from primary, secondary and tertiary centres of care who are actively involved in both the care of patients and research in asthma. The GINA Assembly is a forum for exchange of scientific information and discussions on initiatives to improve asthma care in various countries, focusing on implementation strategies. GINA plays a role in shaping research on the diagnosis and treatment of asthma and informs the development of point of care practice guides and decision support tools. GINA supports the objectives of raising awareness of asthma and improving access to therapy and quality of care for asthmatic patients, in addition to presenting and promoting continuously updated evidence-based treatment approaches for global use.


Assuntos
Asma/terapia , Pneumologia/organização & administração , Adulto , Antiasmáticos/uso terapêutico , Asma/epidemiologia , Criança , Saúde Global , História do Século XX , História do Século XXI , Humanos , Cooperação Internacional , Modelos Organizacionais , National Heart, Lung, and Blood Institute (U.S.) , Pediatria/organização & administração , Guias de Prática Clínica como Assunto , Pneumologia/história , Estados Unidos , Organização Mundial da Saúde
20.
Tunis Med ; 97(11): 1192-1204, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-32173818

RESUMO

AIM: To describe the bibliometric characteristics of Tunisian publications on respiratory tract diseases, during the quinquennium 2010-2014. METHODS: This is a descriptive bibliometric study of respiratory medicine publications, indexed in "Medline", based on their MSDSs. All included articles were written by Tunisian researchers regardless of their position in the list of co-authors. The topics of the publications were explored through their "major" and "generic" keywords. RESULTS: A total of 340 publications was captured in Medline. These articles were co- authored by 218 authors in first position and 163 in last position. They were signed by pulmonologists, in first and last position respectively in 21.5% and 22.4% of articles. The A. Mami Hospital was the major affiliation of the first authors in 19.7% of the publications. These articles were published by 138 journals including "La Tunisie Medicale" in 11.8% of cases. They were "case reports" and written in English respectively in 44.4% and 54.1% of cases. Among 639 major keywords indexing, three were dominant: «Lung Neoplasms¼ (Tumeurs du poumon), «Chronic Obstructive Pulmonary Disease¼ (Broncho-pneumopathie chronique obstructive) and «Tuberculosis, Pulmonary¼ (Tuberculose pulmonaire), in 13.5%, 10.3% and 7.4% of articles respectively. CONCLUSION: Tunisian research on respiratory tract diseases has been thematically concordant with the public health needs. However, it has often been of low-level evidence and published in low-impact factor journals.


Assuntos
Bibliometria , Pesquisa Biomédica/estatística & dados numéricos , Publicações/estatística & dados numéricos , Editoração/estatística & dados numéricos , Pneumologia/estatística & dados numéricos , Doenças Respiratórias , Bibliometria/história , Pesquisa Biomédica/história , Pesquisa Biomédica/métodos , Pesquisa Biomédica/tendências , História do Século XXI , Humanos , Fator de Impacto de Revistas , Publicações/história , Publicações/provisão & distribuição , Publicações/tendências , Editoração/história , Editoração/tendências , Pneumologia/história , Pneumologia/tendências , Doenças Respiratórias/epidemiologia , Doenças Respiratórias/terapia , Faculdades de Medicina/história , Faculdades de Medicina/estatística & dados numéricos , Faculdades de Medicina/tendências , Tunísia/epidemiologia
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